LONGEVITY: The Science of Aging and How to Turn On Your Longevity Genes to Live Longer

Dr. Rajsree Nambudripad, MD is board-certified in Internal Medicine and founder of OC Integrative Medicine in Fullerton, California. In this video, Dr. Rajsree explains the science of aging and all the factors that affect your longevity, from genetics, to diet, exercise, exposures, and lifestyle. What’s the difference between Lifespan and Healthspan? Biological Age vs. Chronological Age? What are the hallmarks of aging? Learn about Sirtuins, AMKP, and mTOR, and Autophagy and how they impact your longevity. How does the gut microbiome impact your Longevity? How does chronic inflammation affect Longevity? She reviews the latest science on Diet, Lifestyle, and Supplements to promote health and longevity. 00:00 Introduction 00:42 Lifespan vs. Healthspan 01:31 Outward Signs of Aging 01:57 Proactive and Preventative Approach to Health and Longevity 02:20 Key Lab Biomarkers 03:45 Chronological Age vs. Biological Age 04:18 Supercentenarians 04:31 Factor Influencing Longevity 05:03 Hallmarks of Aging 08:23 Epigenetic Clock 08:59 Sirtuins, AMPK, and mTOR 13:30 Autophagy 14:58 Time Restricted Eating 16:00 Gut Microbiome and Longevity 17:19 Inflammation and Longevity 17:48 Inflammaging 18:43 Sugar and Advanced Glycation Endproducts 20:18 David Sinclair, PhD and Information Theory of Aging 20:48 Yamanaka Genes (Fountain of Youth Genes) 21:14 The Future: Gene Therapy and Senolytics 22:22 Blue Zones 23:47 Diet: Key Principles 25:35 Intermittent Fasting 26:31 Exercise 27:20 Hormesis 28:09 Supplements to Improve Your Healthspan 29:53 Berberine for Insulin Resistance 30:42 Sleep 31:02 Minimize Exposure to Toxins 31:44 Relationships with People 32:17 Case Example: Mike 32:40 Key Points ➡️Watch Dr. Rajsree’s video on Autophagy: ➡️ Watch Dr. Rajsree’s video on Insulin Resistance (Paleo Diet): ➡️ Watch Dr. Rajsree’s video on Clean Keto Diet: 🧡 Shop for Supplements by Dr. Rajsree: ⭐Learn more about her practice here: 💙 Facebook: 💚 Instagram: 💌 Sign up for Dr. Rajsree’s weekly newsletter: 📦Dr Rajsree’s Amazon Favorites: This information, including but not limited to, text, graphics, images and other material contained on this video and website are for informational and educational purposes only. No material in this video is intended to be a substitute for professional medical advice, diagnosis, treatment, or medical supplement approved by the Food and Drug Administration. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician. Never disregard professional medical advice or delay in seeking it because of something you have seen in this video. No physician-patient relationship is created by this video or the information provided. Furthermore, neither Rajsree Nambudripad, MD or any contributor to this video, makes any representations, express or implied, with respect to the information provided herein or to its use.