Sciatic nerve: branches, course and clinical significance - Human Anatomy | Kenhub

The sciatic nerve is the largest peripheral nerve in the body, and extends from the lower end of the spinal cord, through the thigh, before dividing just above the knee joint. Time to test your knowledge on the sciatic nerve: Oh, are you struggling with learning anatomy? We created the ★ Ultimate Anatomy Study Guide ★ to help you kick some gluteus maximus in any topic. Completely free. Download yours today: The sciatic nerve is a large, bilateral nerve which is formed from the anterior and posterior divisions of spinal nerves L4, L5, S1, S2, and S3. It is the largest branch of the lumbosacral plexus. The sciatic nerve proper innervates the proximal parts of the hamstring muscles, which are the semitendinosus, semimembranosus and biceps femoris muscles. In addition, it also supplies innervation to the ischial component of adductor magnus. After the nerve bifurcates, it innervates the long head of biceps femoris, semi