Key terms
Term Meaning
Pedigree Chart that shows the presence or absence of a trait within a family across generations
Genotype The genetic makeup of an organism (ex: TT)
Phenotype The physical characteristics of an organism (ex: tall)
Dominant allele Allele that is phenotypically expressed over another allele
Recessive allele Allele that is only expressed in absence of a dominant allele
Autosomal trait Trait that is located on an autosome (non-sex chromosome)
Sex-linked trait Trait that is located on one of the two sex chromosomes
Homozygous Having two identical alleles for a particular gene
Heterozygous Having two different alleles for a particular gene
Pedigrees
Pedigrees are used to analyze the pattern of inheritance of a particular trait throughout a family. Pedigrees show the presence or absence of a trait as it relates to the relationship among parents, offspring, and siblings.
Pedigrees represent family members and relationships using standardized symbols.
By analyzing a pedigree, we can determine genotypes, identify phenotypes, and predict how a trait will be passed on in the future. The information from a pedigree makes it possible to determine how certain alleles are inherited: whether they are dominant, recessive, autosomal, or sex-linked.
To start reading a pedigree:
Determine whether the trait is dominant or recessive. If the trait is dominant, one of the parents must have the trait. Dominant traits will not skip a generation. If the trait is recessive, neither parent is required to have the trait since they can be heterozygous.
Determine if the chart shows an autosomal or sex-linked (usually X-linked) trait. For example, in X-linked recessive traits, males are much more commonly affected than females. In autosomal traits, both males and females are equally likely to be affected (usually in equal proportions).
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