What is the normal range of CAG repeats in the HTT gene in unaffected individuals?
The normal range of CAG repeats in the HTT gene in unaffected individuals is between 5 to 26 repeats. This range represents the number of times the cytosine-adenine-guanine (CAG) sequence is repeated within the gene, and within this range, the HTT gene functions normally without leading to Huntington’s disease. Individuals with CAG repeat numbers in this range do not typically develop the symptoms associated with Huntington’s disease, as the length of the CAG repeat within this range does not produce the abnormal form of the huntingtin protein that causes the disease’s neurological symptoms.
Problem:
What is the normal range of CAG repeats in the HTT gene in unaffected individuals?
A) 5-26
B) 27-35
C) 36-39
D) 40-180
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