How to find percent of the bases in DNA (Chargaff’s rule)

Chargaff’s rules state that DNA from any cell of all organisms should have a 1:1 ratio (base Pair Rule) of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. Chargaff rule: The rule that in DNA there is always equality in quantity between the bases A and T and between the bases G and C. (A is adenine, T is thymine, G is guanine, and C is cytosine.) Named for the great Austrian-American biochemist Erwin Chargaff (1905-2002) at Columbia University who discovered this rule. Also known as Chargaff’s ratios. Chargaff later said: “This observation of complementarity, later called Chargaff’s ratios, was essential to the solution of DNA’s structure. In hindsight, the complementary pairing of the nucleotides powerfully suggested that a DNA molecule could break into two parts. Only complementary bases could form bonds and line up in place in a new DNA strand.“ #Adenine #Guanine #Citosine #thymine #genetics #ChargaffsRule #DNA #purine #Cytosine #dnaReplication #chargaffsRuleOfDna #chargaffsRuleProblems #watsonAndCrick #chargaffsRuleExplained #dnaBasesPairing #complementaryBasePairing #DNASequence #dnaComplementarySequence #dnaSequenceComplementaryStrand #andThymine #dnaSemiConservativeReplication #replicationFork #dnaReplicationSong #dnaTranscription #initiation #elongation #termination