Ep 125- How Do Nerve Growth Factor Inhibitors Transform Veterinary Pain Management?
This episode is a snippet from the late 2023 Veterinary Pain Management Workshop hosted by IVDI, which offers a deep dive into nerve growth factor inhibitors, focuses on the cutting-edge therapeutic agents, Salencia for cats and Librella for dogs, addressing their mechanism and impact on pain management. Dr. Mark Epstein, a renowned pain management expert, shares insights from a 2023 workshop, breaking down complex mechanisms and their practical applications in clinical settings.
Main Talking Points:
Introduction to Nerve Growth Factor (NGF) and its inhibitors.
The biology and impact of NGF on pain pathways.
Clinical use and observations with Silencia in cats and Labrella in dogs.
Potential concerns and ongoing questions about NGF inhibitors.
Co-administration with NSAIDs and its implications.
Interesting Quotes:
“NGF is largely responsible for amplifying neurogenic inflammation, making it a prime target for therapeutic intervention.“
“Silencia and Labrella offer significant improvements in mobility and quality of life for cats and dogs suffering from osteoarthritis.“
Timestamps:
0:00 - Introduction to the episode
1:30 - Speaker introduction: Dr. Mark Epstein
2:00 - Overview of nerve growth factor inhibitors
4:00 - The science behind NGF and pain management
6:00 - Clinical observations with Silencia and Labrella
8:00 - Addressing concerns and unanswered questions
9:30 - Discussion on co-administration with NSAIDs
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This episode sheds light on the pivotal role of nerve growth factor inhibitors in managing chronic pain in pets. Dr. Mark Epstein’s expertise offers a comprehensive understanding of how these inhibitors work, their clinical benefits, and the nuanced considerations in their application.
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