The Glycocalyx: An Overriding Don’t Eat Me Barrier / Curr. Biol., Oct. 22, 2020 (Vol. 31, Issue 1)

Imbert et al. report that ligands that stimulate phagocytosis can be obscured by the glycocalyx of pathogenic and malignant targets. Removal of these barriers enhances phagocytic efficiency and facilitates target clearance. The results shed light on physical barriers that modulate phagocytosis. Check out the paper at (20)31495-0. . Imbert, A. Saric, K. Pedram, C.R. Bertozzi, S. Grinstein, and S.A. Freeman (2020). An Acquired and Endogenous Glycoc