Polyarteritis Nodosa and Kawasaki Disease (Medium Vessel Vasculitis) - Symptoms, pathophysiology

Buy Images here: “Medium Vessel vasculitis. Vasculitis is inflammation of the blood vessels resulting in damaged vessels leading to potential complication such as tissue ischaemia from lumen narrowing or from thromboembolic events from platelet consumption during vessel repair. Primary vasculitides are classified into the size of the blood vessels affected; large vessel, medium vessel and small vessel vasculitis. The medium vessel vasculitis includes polyarteitis nodosa and Kawasaki disease Polyarteitis nodosa is a rare systemic necrotising vasculitis targeting medium sized arteries. PAN has distinct features with particular involvement, vasculitis of the renal and visceral arteries. It is associated with HBV, mononeuritis multiplex and renal infarcts. There is no lung involvement, oesinophils are normal and there is absence of Antineutrophil cytoplasmic antibodies. Kawasaki disease is a uncommon systemic vasculitis disease affecting mainly children under the age o