Hardy-Weinberg law and Allele frequency calculations
The Hardy-Weinberg law rests on these assumptions:
•The population under study is large, and matings are random with respect to the locus in question.
•Allele frequencies remain constant over time because of the following:
•There is no appreciable rate of new mutation.
•Individuals with all genotypes are equally capable of mating and passing on their genes; that is, there is no selection against any particular genotype.
•There has been no significant immigration of individuals from a population with allele frequencies very different from the endogenous population.
A population that reasonably appears to meet these assumptions is considered to be in Hardy-Weinberg equilibrium.
Problems:
Which of the following violate the assumptions of Hardy-Weinberg equilibrium?
A) Little or no migration
B) No selection
C) Small population size
D) random mating
E) No mutation
In a human population, the genotype frequencies at one locus are 0.5 AA, 0.4 Aa, and 0.1 aa. The frequency of the A allele in this population is:
A)
B)
C)
D)
E)
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