Here is how anticancer vacines are produced.
Cancer cells express tissue unspecific proteins. These out-of-place proteins may be recognized by the immune system as inappropriate or “non-self”, though the natural immune responses to cancer-associated antigens is often weak, as these types of antigens are not entirely foreign to the body.
How vacines are made? Scientists grow cells with these target proteins sometimes such organisms as bacteria used, then harvest them, purify antigens and inject to the pacient along with adjuvant.
For a cancer-associated antigen to make a good vaccine target, it must be recognized by the immune system and be absent or nearly absent in normal tissue, present only in normal tissues that are not essential for health, or present only in tissues that cannot be accessed by immune cells. This ensures that when the vaccine is given, the immune response only damages and kills cancer cells, and not healthy cells in the body.
While most cancer-associated antigens are unique to a patient, some are frequently present in certain cancer types. For this cancer-associated antigens, vaccines can potentially be prepared ahead of time, allowing for fast and cost-effective treatment.
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