In DVT, there is the potential danger of a blood clot breaking free and travelling with the blood stream. As a consequence, the clot is able to reach the heart. From there, it can be transported to the arteries of the lungs, where it may become stuck in the smaller vessels, causing a pulmonary embolism (PE).
References:
Goldhaber SZ, Morrison RB. Pulmonary Embolism and Deep Vein Thrombosis. Circulation 2002; 106: 1436-38
Spencer FA, Emercy C, Lessard D, et al. The Worcester Venous Thromboembolism study: a
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