What Student Need to Know about Imaging of Reticuloendothelial Disorders In Radio Diagnosis.
The reticuloendothelial system (RES) plays an important role in inflammatory responses, antigen presentation, and immunoregulatory networks depression of its function is likely to weaken the host defense. Since the hepatic RES contains the largest number of fixed tissue macrophages (Kupffer cells) and accounts for more than 80% of the entire RES impairment of the liver has a major influence on RES function. Bacterial infections is the most common complication of chronic liver injury and after partial hepatectomy; therefore the precise estimation of RES function is very important.
Dynamic SPIO-enhanced MR imaging with two-compartment modeling can provide information on RES function on both a cell number and receptor function level. This may allow more accurate diagnosis or therapy monitoring in liver disease, and may provide insight into possible therapeutic mechanisms.
Liver imaging with gadolinium contrast enhanced MRI is sometimes not sufficient for a reliable diagnosis of liver lesions. For this
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