Peyronie’s disease Nonsurgical interventions

Peyronie’s disease (PD) is a condition characterized by penile pain, curvature, shortening and sexual dysfunction. The condition itself is common ― some studies suggest that 8% to 10% of men have signs or symptoms of PD. This condition was once thought to be a condition primarily impacting middle-aged men, but Mayo Clinic specialists routinely see the condition present in patients as young as teenagers and in many patients in their 70s and 80s, as well. The leading hypothesis is that PD is a wound healing disorder of the penis that occurs in genetically predisposed men in response to penile trauma. Ultimately, a scar (plaque) forms on the tunica albuginea of the penis, preventing the normal highly elastic tunical fibers from expanding in the affected area as the penis fills with blood during an erection. This disorder results in the classic changes to the shape and appearance of the penis, such as curvature. “The majority of men who present with PD do not recall a specific episode