Isometric games often use hand-drawn 2D sprites to add depth to a game without having to deal with full 3D rendering.
In this video, I cover how it works, the math you need to render isometric sprites on the screen, and how to find the isometric tile from a screen coordinate.
0:00 Intro
0:21 Orthographic projection
1:16 Tiling a sprite
1:40 Transforming tile coordinate to screen
2:55 Accounting for sprite size
3:39 Correcting offsets
4:00 Transforming screen coordinate to tile
4:46 Adding depth
4:52 Outro
Music: Snake Hips - Lucas Pittman (via )