Virology Lectures 2020 #2: The Infectious Cycle

The complete course of events in a virus infected cell is known as the infectious cycle. We discuss the different parts of the infectious cycle and how to study them, including assay of infectious virus particles by plaque assay, multiplicity of infection, and the particle to pfu ratio. Physical methods for detecting viruses include hemagglutination, serological techniques, polymerase chain reaction, and high-throughput sequencing. We show how these methods were used to identify the new coronavirus that has