An organic chemistry minilecture on the Enantioselective Total Synthesis of Dysiherbols A, C, and D by Shengkun Hu and Yefeng Tang*. It utilizes a highly unusual [1,2]-Anionic Rearrangement / Cyclopropane Fragmentation reaction to form the dysiherbol framework that can be easily functionalized to synthesize multiple members of this family.
SUPPORT THE CHANNEL ON PATREON:
NMR Spectroscopy in music:
J. New Music Res. 2021, 50:5, 487-501
Socials:
References:
J. Am. Chem. Soc. 2022, 144, 19521−19531 (This work)
J. Nat. Prod. 2016, 79, 2, 406–411 (Discovery)
Chin. J. Nat. Med. 2022, 20, 148-154 (Discovery)
Angew. Chem., Int. Ed. 2021, 60, 13807−13813 (Previous synthesis/ Structural revision)
Angew. Chem., Int. Ed. 2021, 60, 14915−14920 (Previous synthesis/ Structural revision)
Theoret. Chim. Acta , 1977, 45, 283–300 (Quinone- alkene photocycloadditions)
Tetrahedron Lett. 1988, 29,2761−2764 (Alkene isomerisation)
1 view
758
225
2 months ago 00:07:42 1
Total Synthesis of Hypersampsone M
2 months ago 00:05:54 2
Ambient jam with the Soma Terra and Soma Cosmos
2 months ago 00:04:26 1
Josef Hoffmann, Architect
3 months ago 00:07:30 1
John B - Sax Therapy (Remix) (1997)
3 months ago 00:08:46 1
“Breaking Barriers: The Total Synthesis of Palau’amine Explained“ (3D Visualization)
3 months ago 00:00:53 34
UCHRONIA Teaser #2
3 months ago 00:00:54 50
UCHRONIA Teaser
4 months ago 00:27:36 1
“That’s just noise.“ (why we left classical music)
4 months ago 00:05:18 1
12 D Shield Building Technique
4 months ago 00:31:17 1
DREAM BUILD MTB - Santa Cruz Megatower - NEW LOOK WORKSHOP!
5 months ago 00:09:36 1
11-Step and Scalable Total Synthesis of Hamigeran M Enabled by Five C−H Functionalizations
5 months ago 00:04:20 1
livMatS Biomimetic Shell Project Video
8 months ago 00:35:43 25
Origin Overview - Our BIGGEST and BEST cinematic pack is HERE!
8 months ago 00:02:58 66
Origin - Cinematic Opus Magnum
8 months ago 00:28:10 1
Epic First Cocaine Synthesis in 25 Steps (Educational)